A Mechanism for Somatic Brain Mosaicism
نویسندگان
چکیده
Double-strand break repair is required for neural development, and brain cells contain somatic genomic variations. Now, Wei et al. demonstrate that neural stem and progenitor cells undergo very frequent DNA breaks in a very restricted set of genes involved in neural cell adhesion and synapse function.
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ورودعنوان ژورنال:
- Cell
دوره 164 شماره
صفحات -
تاریخ انتشار 2016